Diaper rash is one of the most common skin concerns for infants and toddlers, but that doesn’t mean it’s always simple to treat. Whether you’re dealing with a mild flare-up or a rash that just won’t go away, it’s important to understand when to try home care and when to turn to a professional for diaper rash treatment.
At the Dermatology & Cutaneous Surgery Institute (DCSI), we specialize in treating a full range of pediatric skin conditions, including persistent and severe diaper rashes. With dermatology offices conveniently located in Palm Beach County, our team helps families throughout South Florida manage their child’s skin health with confidence and care.
What Causes Diaper Rash?
Diaper rash can occur for a variety of reasons, most often due to prolonged exposure to moisture or friction from diapers. Urine and stool can change the skin’s pH level, making it more prone to irritation and inflammation. This breakdown in the skin barrier leaves your baby vulnerable to redness, rash, and sometimes even infection.¹
In addition to wetness, common causes of diaper rash include reactions to baby wipes or soaps, new foods that affect stool acidity, and antibiotic use that disrupts skin balance.² In some cases, a diaper rash may be triggered by yeast or bacteria growing in a warm, moist diaper area.
In some countries, diaper rash is also known as “nappy rash,” but the causes and treatments remain the same. While many parents start with barrier creams or over-the-counter ointments, it's not uncommon for certain rashes to worsen or resist basic treatment. That’s when a closer look is needed. You can also learn more about other conditions that may resemble diaper rash in our guide on types of rashes.
When a Baby Rash Doesn’t Go Away
If you’ve been trying diaper rash creams for a few days and see no improvement, you’re not alone. A baby's rash not going away could mean the rash is actually a symptom of something else, such as eczema, seborrheic dermatitis, or an allergic reaction.
Our dermatology team specializes in diagnosing complex or recurring rashes in children. We’ll evaluate possible triggers, review your baby’s skin routine, and determine whether prescription treatment or further testing is necessary. For a broader overview of chronic or persistent pediatric conditions, you can visit our full pediatric skin conditions guide.
What Does a Severe Diaper Rash Look Like?
Most diaper rashes are mild, but sometimes, they can become severe and develop quickly. So, what does a severe diaper rash look like? These rashes may appear bright red, swollen, or blistered. The skin might ooze, crust, or even bleed. Your baby may cry during diaper changes or seem more irritable than usual.
These symptoms could point to a more advanced skin condition or an underlying infection. A fungal diaper rash, for example, tends to spread to skin folds and can’t be treated effectively with standard barrier creams. These types of rashes often require an antifungal medication to resolve. If you notice any of these warning signs or if you’re unsure what’s causing the rash, don’t hesitate to reach out to a specialist.
In rare cases, rashes that resemble diaper rash may be early signs of psoriasis, particularly if they persist for weeks and resist treatment. Learn more about how that condition appears in infants and toddlers in our article on what psoriasis is.
Professional Diaper Rash Treatment From DCSI
When home remedies aren’t enough, our providers at DCSI offer individualized diaper rash treatment plans tailored to your baby’s skin. For mild irritation, we may recommend switching to fragrance-free products or using a protective ointment after each change. If the rash is more persistent or shows signs of fungal involvement, we can prescribe medicated creams or evaluate for allergic triggers.
We work with parents to uncover the root cause, prevent future flare-ups, and protect your child’s delicate skin from further irritation. Our dermatology offices are located in Palm Beach County, offering trusted dermatology services in South Florida for children of all ages.
How to Help Prevent Diaper Rash
The best way to handle diaper rash is to prevent it whenever possible. Keeping your baby’s skin clean and dry is essential. Frequent diaper changes and using gentle, fragrance-free wipes can make a big difference. Many parents apply a thick layer of barrier cream to protect the skin and reduce friction, especially at bedtime.
Letting the skin breathe during diaper-free time can also help. And if you’re introducing new foods, keep an eye out for any signs of irritation, as changes in stool acidity can sometimes trigger diaper rash. Even with the best care, some babies are more prone to irritation and may need dermatologic support to stay rash-free.
Frequently Asked Questions About Diaper Rash
What does a severe diaper rash look like?
A severe diaper rash may be deep red, blistered, oozing, or bleeding. It can cause pain or fussiness during changes and might spread beyond the diaper area. These symptoms often indicate that the rash needs medical attention.
When should you see a dermatologist for diaper rash?
If your child’s rash doesn’t improve within three to five days, or if it becomes worse with home care, it’s time to consult a specialist. Persistent or recurring rashes often benefit from a proper diagnosis and prescription treatment.
Can a food allergy or a new formula cause diaper rash?
Yes. New foods can alter your baby’s stool, making it more acidic and irritating to the skin. Formula changes may also lead to digestive changes that increase the risk of diaper rash. If you suspect a food-related trigger, speak with a healthcare provider.
Is it normal for a diaper rash to bleed or peel?
Bleeding, peeling, or open sores are not typical and may point to a more serious issue. These rashes may be infected or caused by an underlying skin condition. Medical care is recommended in these cases.
When should you see a dermatologist for diaper rash?
If the rash is spreading, painful, recurring, or not responding to treatment, it’s a good idea to schedule an evaluation. A dermatologist can help determine the root cause and provide lasting relief for your baby’s skin.
Diaper Rash Treatment in Palm Beach County
If your baby is struggling with an uncomfortable rash that won’t improve, professional help is just a call away. Contact Dr. Mounir M. Wassef and the DCSI team for expert diaper rash treatment from a trusted South Florida provider.
We offer solutions for fungal rashes, allergies, sensitive skin conditions, and more. Visit our pediatric dermatology services page to learn how we care for our youngest patients, and don’t forget to check out our dermatitis blog for helpful tips and insights on keeping your baby’s skin healthy.
Sources
- Diaper rash - Symptoms and causes. Mayo Clinic. https://www.mayoclinic.org/diseases-conditions/diaper-rash/symptoms-causes/syc-20371636. Published March 4, 2023. Accessed July 2025.
- Diaper rash. KidsHealth. https://kidshealth.org/en/parents/diaper-rash.html. Published May 2023. Accessed July 2025.